Assessment of Sleep Benefit in Parkinson's Disease
Assessment of Sleep Benefit in Parkinson's Disease
We showed that the subjective experience of SB in PD is not always related to an actual increase in reported motor function after sleep. Defining SB using either a symptom diary or a questionnaire on subjective experience, probed different aspects of the phenomenon, resulting in only partly overlapping groups. These data suggest that SB may be a more heterogeneous phenomenon than previously thought and that subjective experiences of symptom severity is not necessarily related to actual motor function.
Given its potential clinical relevance as therapeutic intervention, there is now a crucial need for detailed prospective studies using quantitative objective measures of motor performance, in relation to objective assessment of sleep quality. Such studies should also monitor the effects of SB on non-motor symptoms of PD, including cognitive deficits and fatigue, as these may potentially improve in relation to sleep as well.
Conclusions
We showed that the subjective experience of SB in PD is not always related to an actual increase in reported motor function after sleep. Defining SB using either a symptom diary or a questionnaire on subjective experience, probed different aspects of the phenomenon, resulting in only partly overlapping groups. These data suggest that SB may be a more heterogeneous phenomenon than previously thought and that subjective experiences of symptom severity is not necessarily related to actual motor function.
Given its potential clinical relevance as therapeutic intervention, there is now a crucial need for detailed prospective studies using quantitative objective measures of motor performance, in relation to objective assessment of sleep quality. Such studies should also monitor the effects of SB on non-motor symptoms of PD, including cognitive deficits and fatigue, as these may potentially improve in relation to sleep as well.