Mysoline which contain Primidone is used either alone or with other seizure medicines to control generalized tonic-clonic and partial seizures.It is also used to treat myoclonic seizures and other seizure types in people with juvenile myoclonic epilepsy.

Indications:
Mysoline, used alone or concomitantly with other anticonvulsants, is indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy.

Contraindications:
People who have had a condition called porphyria should not take primidone. Furthermore, those who are sensitive to phenobarbital are advised to avoid it, because the body produces phenobarbital when it processes primidone.
Women who are pregnant or may become pregnant, and those who are breast-feeding should be cautious about using primidone. The manufacturer suggests that breast-feeding be discontinued if the baby is unusually sleepy. Other seizure medicines may be a better choice for pregnant women and nursing mothers.

Side effects:

• The most common side effect of primidone particularly with initial use, is fatigue.


• Sleepiness that can be severe, especially when you first start taking Mysoline.

Mysoline may rarely cause blood problems. Symptoms may include:

• fever, swollen glands, or sore throat that come and go or do not go away


• Frequent infections or an infection that does not go away


• tiredness


• shortness of breath

Mysoline may rarely cause allergic reactions. Symptoms may include:

• skin rash


• hives


• sores in your mouth


• blistering or peeling skin

Side effects are generally mild and tend to decrease with time. Other side effects include:

• Unsteadiness ,a spinning sensation (vertigo)


• Nausea,vomiting


• blurred or double vision, drowsiness, depression

Precautions:

• It can make you sleepy or dizzy.


• Do not drink alcohol or take other drugs


• that make you sleepy or dizzy while taking MYSOLINE without first discussing thiswith your healthcare provider.


• Taking this drug with alcohol or drugs that cause sleepiness or dizziness may make your sleepiness or dizziness worse.


• Do not drive, operate heavy machinery, or do other dangerous activities until you know how MYSOLINE affects you.


• It can slow your thinking and motorskills.Do not drive, operate heavy machinery, or do other dangerous activities until you know how MYSOLINE affects you. It can slow your thinking and motorskills.

Dosage & When it is to be taken:

• Adult- PO- Days 1 to 3: 50 mg at bedtime.


• Days 4 to 6: 50 mg two times per day.


• Days 7 to 9: 100mg two times per day.


• Day 10 to maintenance: 125 mg to 250 mg three times per day.

Storage:
Store Mysoline at room temperature between 68 F to 77F (20 C to 25 C) in a tight, light-resistant container. Keep out of the reach of children.