Pain

• While warts themselves do not generally cause pain, the act of freezing them can be quite painful. Cryotherapy involves using liquid nitrogen to freeze the wart. Though this procedure can be completed in just a few minutes at your doctor's office, complete removal of a wart usually requires several painful cryotherapy sessions. Anesthesia may be used for patients who find the process particularly painful. Warts are usually removed after four sessions, with at least one week between sessions. Pain often lasts up to three days after each session, according to WebMD.